What Is The Leading Cause Of Loss Of Biodiversity?

Global Cooling to the level of Ice Ages.  I know of no other single factor which has caused as high die off levels as past ice ages, other than possibly the theoretical K10 meteorite which is believed to have killed off the dinosaurs.

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The leading cause of loss of biodiversity is attributed to climate change. Apart from that the habitat destruction can accelerate the rate of biodivesity loss. Causes like mutaion will take some time to show the effects. But biodiversity is mainly affected by climate change and pollution.

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If your talking about now-a-days by far the biggest cause of loss of biodiversity is destruction of habitat. Global warming has had some affects, and will soon probably be the biggest cause, but at the moment human destruction of habitat is. Pollution is probably the main cause of loss of biodiversity in aquatic environments since these are more susceptible to change.
 
As long as humans don't have any influence, both competition and mutation are natural occurences in ecosystems. Competition will naturally affect biodiversity in some ecosytems, but in the long term it will balance out. Mutation, as long as there are no outside influences such as radioactive chemicals or virus outbreaks will not affect biodiversity in a natural ecosystem.

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