According to Mapquest.com, Kalamazoo, Michigan to Jackson, Michigan via the freeway should take approximately one hour and seven minutes. This is by going I-94 BR E and then I-94 E for 59 miles.
Distance wise, Mapquest.com estimate this journey at 65.5 miles. To improve on these rough estimates, though, follow the link above. Click the Revise links and enter the addresses of your starting and finishing points to update the mileage and timing, and to obtain door-to-door driving directions as well.
There are also links to maps for each leg of the journey, and it is also possible to add in up to ten other destinations along the way and to fine tune the directions for the shortest time or shortest distance (in this case, the shortest distance adds a good 20 minutes to the journey). You can also reverse the route and elect to avoid toll roads, seasonally closed roads and avoid highways.