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Yes, it's not uncommon for siblings from the same litter to mate. It happens with cats, dogs, mice, rats, and many types of animals. It's not a good idea to keep breeding animals from the same litters or within related generations. That's inbreeding and eventually weakens the strain. Genetic defects begin to appear.
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They most definitely will . My cat is about 12 yrs old and his mother is like his sister or something. Weird huh
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