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The Advil contains ibuprofen which is an non steroidal anti-inflammatory drug. The Tylenol 2 contains acetaminophen which is also an analgesic. There are no studies available with the combine use of ibuprofen and acetaminophen. Only studies with aspirin are available. I advise you don't take these two medicines together or with a gap of 2 hours as no scientific support is available. For information, visit TYLENOL
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