I wouldn't you can use cat flea and tick shampoo or bath but don't leave it on longer than 5 to 8 minutes as it will dry their skin by a chemical burn or check with your vet you are going to need a vet very much so for the simple reason ferrets are very different from dogs and cats as they get more diseases and cancers then dogs or cats and they have to have their rabies and distemper shot and get the distemper shot separate from the rabies.