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Yes, use of estrogen can cause headache. Sometimes it can cause migraine headache. Some other side effects of estrogen are
- Weight gain
- Breast tenderness
- Swelling of feet and lower legs
- Breast enlargement
- Confusion
- Yellow eyes and skin
- Unusual tiredness
- Nausea
- Vomiting
- Persistent jerky muscle movements
- Abdominal pain
- Blood filled skin sores
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