I could be on my way to Early Alzheimer's. I have been diagnosed with Mild Cognitive Impairment almost 2 yrs ago. I have Recurrent Major Depression, and I've had about forty ECT treatments; many were bi-lateral. I have been helped very little by anti-depressants, and I have tried them all. I now have holes in my brain. What are the ramifications of this? I have had about 9 Major Depressions.